Secondary tumor results. A–B) a representative H&E section of the lung from the SaOS-2 cohort and its exploded view respectively. C) Macrometastases (white arrows) in a SaOS-2 tumor-bearing mouse lung. D) The lung of a U2OS mouse with no metastasis. E–F) a representative H & E section of the lung from the 143B cohort and its exploded view respectively. The presence of possible osteoid material is indicated with a white arrow. Scale bar = 250 μm (A, D, E), 125 μm (B, F) and 5 mm (C).
